Balicatib(AAE-581) factory supply CAS NO.354813-19-7

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Min.Order: 1 Gram
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Available Specifications:
99%(1-10)Gram100/Gram1USD99%(10-50)Gram200/Gram10USD

Product Details

Keywords

Balicatib factory
354813-19-7
Balicatib(AAE-581) supplier

Quick Details

ProName: Balicatib(AAE-581) factory supply
CasNo: 354813-19-7
Molecular Formula: C23H33N5O2
Appearance: solid
Application: API，Pharmaceutical intermediates
DeliveryTime: 1-2days after the payment
PackAge: 1g to 1kg or as your request
Port: Shanghai, Shenzhen
ProductionCapacity: 500 Kilogram/Month
Purity: 99%
Storage: 2℃-8℃
Transportation: DHL, UPS, FEDEX EMS or as your request
LimitNum: 1 Gram
Residue on Ignition: ≤0.01
Heavy Metal: ≤0.03
Valid Period: 3years

Superiority

We are a leading provider and manufacturer of pharmaceutical and chemical products. Mainly involves API, pharmaceutical intermediates, polypeptide, and natural extract etc。We are capable to supply you with any quantity of the mentioned products with fast and secure delivery to any of your desire address .and any part of world with good prices. . We export products to USA, Canada, Mexico, Brazil, United Kingdom, Japan, Russia, Germany, India, South Africa, Malta, Egypt, Armenia, Australia, Philippines, Belgium, Netherlands, Denmark, Bosnia and Herzegovina ect.

We work hard for getting sustainable development, and making contributions to our society and health industry of human being. Upholding international QC idea, we follow customers’ demands closely, and strive to offer customers stable qualities and excellent service. Through improving comprehensive strength continuously, we are working hard for get sustainable development! We persist in the management policy of People Oriented, and devote ourselves to providing the best products and services. The quality is the future market, the goodwill is the invisible market, the satisfaction of the customers is the eternal market. To center around the customers, providing the first-class products and services. To be guided by the market, create the perfect production and supply system. We welcome all kinds of cooperation with the friends all over the world on the fundamental business principle of "equality, mutual benefit and friendly cooperation”.

Process Capability : After-sale Service : We guarantee good quality products. . 100% refunded if parcel is not delivered or poor quality.

Details

we could support you:

1. best quality products;

2. competitive price in china market,

3. safe and fast shipping;

4. professional technical support;

5. samples order is welcomed

6. HNMR and HPLC will be offered after the order.

We are insisting on the tenet of "quality first, customer top, speed supreme, excellent quality and reasonable price", we would like to cooperate with you!

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Balicatib (Synonyms: AAE581)

Description

Balicatib(AAE-581) is a potent and selective inhibitor of cathepsin K; 10-100 fold more potent in cell-based enzyme occupancy assays than against cathepsin B, L, and S. IC50 value: Target: cathepsin K The cathepsin K inhibitor AAE-581 (balicatib) as the most advanced of them passed Phase II clinical trials in 2005. Eighty adult female Macaca fascicularis underwent bilateral ovariectomies and were dosed twice daily by oral gavage with balicatib at 0, 3, 10, and 50 mg/kg for 18 months (groups O, L, M, H, respectively). Approximately 1 month after treatment initiation, the 50 mg/kg dose was decreased to 30 mg/kg. Twenty animals underwent sham-ovariectomies (group S). Bone mass was measured at 3-6 month intervals. At 18 months, vertebra and femur were collected for histomorphometry.

Molecular Weight

411.54

Formula

C??H??N?O?

CAS No.

354813-19-7

SMILES

CCCN1CCN(C2=CC=C(C(NC3(C(NCC#N)=O)CCCCC3)=O)C=C2)CC1

Shipping

Room temperature in continental US; may vary elsewhere

Storage